Synthesis of poly-(L-azetidine-2-carboxylic acid)

Abstract

Synthesis of poly-(L-azetidine-2-carboxylic acid) has been achieved by polymeric self-condensation of both the pentachlorophenyl and the succinimido-esters of L-azetidine-2-carboxylic acid hydrochloride. Racemization tests have been performed on model compounds and on polymer fractions with nearly identical molecular weights (M_w) isolated from different preparations. The water content of the polymer has been determined from the water-binding isotherm at 23 °C.