The suitability of the p-tolysulphonyl group for protecting the guanidino-system in the synthesis of arginine-containing sequential polypeptides by the 2-hydroxyphenyl ester and pentachlorophenyl ester methods has been demonstrated by syntheses of poly-(L-arginyl-L-alanyl-L-alanine) and poly-(L-arginylglycyl-L-proline).
J. R. Bell, J. H. Jones, D. M. Regester and T. C. Webb, J. Chem. Soc., Perkin Trans. 1, 1974, 1961 DOI: 10.1039/P19740001961
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