Issue 0, 1974

Heterocyclic studies. Part XXXV. Cleavage of fervenulin and 3-methylfervenulin by nucleophiles

Abstract

Treatment of fervenulin {6,8-dimethylpyrimido[5,4-e]-as-triazine-5,7(6H,8H)-dione} and 3-methylfervenulin with primary amines gave 6-(3-alkyl-1-methylureido)-5-methylcarbamoyltriazines by attack at position 7 and cleavage of the 6,7-bond. Reactions with hydrazine and 1,1-dimethylhydrazine similarly gave triazin-6-ylsemicarbazides. Fervenulin and methylhydrazine gave 5,6-diamino-1,3-dimethyluracil and an unknown compound by cleavage of the triazine ring. The 6-(1-methyl-3-alkylureido)-5-methylcarbamoyltriazines were converted by cold nitrous acid into open-chain compounds. 1H N.m.r., mass, and u.v. spectra are tabulated and discussed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1974, 1818-1823

Heterocyclic studies. Part XXXV. Cleavage of fervenulin and 3-methylfervenulin by nucleophiles

J. Clark and M. S. Morton, J. Chem. Soc., Perkin Trans. 1, 1974, 1818 DOI: 10.1039/P19740001818

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements