Pyrrolo[1,2-a][1,3,5]triazine-2,4(1H,3H)-diones. Part II. Synthesis from 3,4-disubstituted 2-aminopyrroles
Abstract
Treatment of 2-aminopyrroles, containing electron-withdrawing groups in positions 3 and 4, with aryl or alkyl isocyanates is shown to yield 3,7,8-trisubstituted pyrrolo[1,2-a][1,3,5]triazine-2,4(1H,3H)-diones. The intermediacy, in the reaction, of either (pyrrol-2-yl)ureas or 1-amido-2-aminopyrroles is discussed.