Microbiological hydroxylation. Part XII. Comparative behaviour of D-homogonane (perhydrochrysene) ketones and steroids
Abstract
rac-D-Homogonanes, with one and two oxygen substituents in positions comparable to those of certain C19 steroids have been synthesised. When these C18 compounds, lacking the steroid angular methyl groups, are incubated with cultures of Calonectria decora and Rhizopus nigricans, the patterns of hydroxylation observed are closely analogous to those with the structurally related steroids.