Issue 0, 1974

Synthesis of aziridines by reduction of oximes and O-alkyl oximes with sodium dihydrobis-(2-methoxyethoxy)aluminate

Abstract

Reduction of aryl ketone oximes and their O-alkyl derivatives with sodium dihydrobis-(2-methoxyethoxy)aluminate, gives aziridines in up to 90% yield. Stereochemical relationships and mechanisms for the formation of amines and cis- and trans-disubstituted aziridines are discussed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1974, 1294-1299

Synthesis of aziridines by reduction of oximes and O-alkyl oximes with sodium dihydrobis-(2-methoxyethoxy)aluminate

S. R. Landor, O. O. Sonola and A. R. Tatchell, J. Chem. Soc., Perkin Trans. 1, 1974, 1294 DOI: 10.1039/P19740001294

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