The configuration at C-13a in tylophorine (I) has been established as S. Ozonolysis of tylophorine gave (S)-pyrrolidine-2-acetic acid identical with a sample synthesized from (S)-proline. The absolute configuration of analogous alkaloids of the group can be deduced by comparison of their o.r.d. spectra with that of tylophorine.
T. R. Govindachari, T. G. Rajagopalan and N. Viswanathan, J. Chem. Soc., Perkin Trans. 1, 1974, 1161 DOI: 10.1039/P19740001161
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...