SCHEDULED MAINTENANCE:
[1-(D-2-Hydroxy-3-mercaptopropanoic acid)]oxytocin was synthesized by azide coupling of O-benzyl-N-(D-3-benzylthio-2-hydroxypropanoyl)-L-tyrosine hydrazide with a heptapeptide. The hormone analogue had an uterotonic activity of 27·3 i.u. mg–1 and did not bind to neurophysin.
M. Wälti and D. B. Hope, J. Chem. Soc., Perkin Trans. 1, 1974, 202 DOI: 10.1039/P19740000202
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