Constitution and absolute configuration of austdiol, the main toxic metabolite from Aspergillus ustus
Abstract
The fungal metabolite austdiol, elaborated by Aspergillus ustus, has been identified as (7R,8S)-7,8-dihydro-7,8-dihydroxy-3,7-dimethyl-6-oxo-6H-2-benzopyran-5-carbaldehyde. The absolute configuration was deduced by the ‘partial resolution’ method of Horeau.