Cyclohexyl isocyanide reacts with nucleoside 2′(3′)-phosphates to afford 2′,3′-cyclic phosphates or with a mixture of phosphomonoesters (viz., 2′,3′-di-O-acetyluridine 5′-phosphate or phenyl phosphate) and alcohols to give the corresponding phosphodiesters in ca. 90% yields.
Y. Mizung and J. Kobayashi, J. Chem. Soc., Chem. Commun., 1974, 997 DOI: 10.1039/C39740000997
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