Rate enhancements attributable to hydrophobic interaction of linear alkyl groups with a steroidal enzyme model have been measured and are much smaller than the values reported previously for less well defined enzyme model systems, but are in satisfactory agreement with independent evaluations of these interactions.
J. P. Guthrie and Y. Ueda, J. Chem. Soc., Chem. Commun., 1974, 991 DOI: 10.1039/C39740000991
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