The β-lactam fused thiadiazine ylide (1) undergoes quantitative thermal rearrangement to the thiadiazine ring-opened β-lactam (2), which can then undergo β-lactam cleavage rections with a variety of nucleophilic reagents to give dipeptides [(3)–(5)].
M. M. Campbell and G. Johnson, J. Chem. Soc., Chem. Commun., 1974, 974 DOI: 10.1039/C39740000974
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