Upon the validity of partial rate factors based on isomer distributions in the phenylation of 4-methylpyridine with benzoyl peroxide

Abstract

The homolytic phenylation of 4-methylpyridine with benzoyl peroxide in refluxing benzene has been studied. The reactivities of the two nuclear positions of 4-methylpyridine towards attack by phenyl radicals depend on the benzoyl peroxide concentration used. The isomer ratio remains constant when reactions were carried out in presence of nitrobenzene. The significance of these results is discussed.