Issue 12, 1973

The kinetics and mechanism of the electrophilic substitution of heteroaromatic compounds. Part XXXIV. The hydrogen-exchange rates of methylpyrazoles

Abstract

Acid-catalysed hydrogen-exchange rates are recorded for 1-methylpyrazole and for its 3-, 4-, and 5-mono- and 3,4-, 3,5-, and 4,5-dimethyl derivatives, together with those for the corresponding 2-methylpyrazolium cations. The rates have been extrapolated to give rate constants at 100° and pH 0: these are discussed with reference to the effect of the methyl groups and of the two cyclic pyrazole nitrogen atoms on electrophilic substitution rates.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 2, 1973, 1675-1680

The kinetics and mechanism of the electrophilic substitution of heteroaromatic compounds. Part XXXIV. The hydrogen-exchange rates of methylpyrazoles

S. Clementi, P. P. Forsythe, C. D. Johnson and A. R. Katritzky, J. Chem. Soc., Perkin Trans. 2, 1973, 1675 DOI: 10.1039/P29730001675

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements