Issue 0, 1973

Stereochemical studies on aromatic α-alkyl-α-amino-acids. Part III. Absolute configuration of 2-amino-2-phenylbutyric acid

Abstract

(+)-2-Formamido-2-phenylbutyric acid has been converted into (–)-2-phenyl-2-p-tolylsulphonylaminobutane, which was also obtained by to sylation of (-)–(S)-2-amino-2-phenylbutane. This correlation proves the S-configuration of (+)-2-amino-2-phenylbutyric acid. Application of stereochemical optical rotation shift rules confirms this assignment.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1973, 1866-1869

Stereochemical studies on aromatic α-alkyl-α-amino-acids. Part III. Absolute configuration of 2-amino-2-phenylbutyric acid

J. A. Garbarino, J. Sierra and R. Tapia, J. Chem. Soc., Perkin Trans. 1, 1973, 1866 DOI: 10.1039/P19730001866

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