Issue 0, 1973

N-alkylation of thymine and uracil with trialkyl phosphates

Abstract

Treatment of thymine and uracil under appropriate conditions with trimethyl, triethyl. or tri-n-butyl phosphate has given 1-methylthymine (80%). 1,3-dimethylthymine (87%), 1 -ethylthymine (80%), 1-n-butylthymine (40%), 1-methyluracil (80%), 1,3-dimethyluracil (75%), and 1-ethyluracil (35%).

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1973, 391-392

N-alkylation of thymine and uracil with trialkyl phosphates

K. Yamauchi and M. Kinoshita, J. Chem. Soc., Perkin Trans. 1, 1973, 391 DOI: 10.1039/P19730000391

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