The chemistry of fungi. Part LXVIII. Absolute configuration of 2-iso-propyl-2-methyl-succinic and -glutaric acids: some resultant stereo-chemical corrections
(+)-2-Isopropyl-2-methylglutaric acid has been prepared from (+)-2-isopropyl-2-methylsuccinic acid. The absolute configuration of these acids has been defined as S by an X-ray crystallographic examination of (+)-rubidium 1-methyl 2-isopropyl-2-methylsuccinate.
The repercussions of this definition upon the previously accepted absolute stereochemical assignments of numerous substances related to these acids are discussed.