Issue 16, 1973

An alkali-labile substituted benzyloxycarbonyl amino-protecting group

Abstract

4-Isopropyloxycarbonyloxybenzyloxycarbonyl, Z(4-PriOCO), a new amino-protecting group stable under the conditions which cause cleavage of the t-butoxy-carbonyl and 2-(p-biphenylyl)isopropyloxycarbonyl groups, can be removed in a slightly alkaline medium via a 1,6-elimination, by hydrogenolysis, or by HBr in acetic acid.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1973, 593-594

An alkali-labile substituted benzyloxycarbonyl amino-protecting group

M. Wakselman and E. Guibé-Jampel, J. Chem. Soc., Chem. Commun., 1973, 593 DOI: 10.1039/C39730000593

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements