Spontaneous hydroxylation of a 1,5,7-trisubstituted 4-oxo-1,4,5,8-tetrahydro-1,8-naphthyridine
Abstract
Spontaneous hydroxylation, in the presence of air, of 5-butyl-1-ethyl-7-methyl-4-oxo-1,4,5,8-tetrahydro-1,8-naphthyridine (III) into 5-butyl-1-ethyl-6-hydroxy-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine (IV) is described.