X-Ray crystal structure determination of a new alkaloid, daphnilactone A, C23H35O2N

Abstract

The structure of the title compound (I) has been determined from three-dimensional diffractometer data. The structure was determined directly by the symbolic addition procedure, and refined by least-squares methods to R 5·8% for 2014 observed non-zero reflections. The crystals are orthorhombic, space group P2₁2₁2₁ with Z= 4 in a unit cell of dimensions: a= 14·258, b= 13·481, c= 10·090 Å. The ring system of this alkaloid is novel but it has a 2-azabicyclo[3,3,1]nonane ring, a common moiety in daphniphyllum alkaloids.