Persulphate oxidations. Part VIII. Oxidation of arylthio-, arylsulphonyl-, and arylamino-acetic acids

Abstract

Persulphate oxidation of (biphenyl-2-ylthio)acetic acids gave ArSĊR₂ radicals which mainly cyclised to give monomeric and dimeric thiopyrans. The corresponding sulphonylacetic acid was less reactive giving a lower yield of cyclised product. Oxidation of (biphenyl-2-ylamino)acetic acids yielded only traces of cyclised products owing to the ease with which the intermediate ArNRĊH₂ radicals were oxidised further to cations.