Peptide sequences corresponding to units 1–5 (C chain) and positions 13–16,15–17, 17–19, and 20–23 (A chain) of the fibrinogen molecule have been synthesised. The use of the 4-picolyl ester group for carboxy-terminal protection has simplified the synthesis of protected intermediates.
D. J. Schafer, J. Chem. Soc., Perkin Trans. 1, 1972, 1452 DOI: 10.1039/P19720001452
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