Reaction of phenylacetonitrile anion with sulphites: a novel isothiazole synthesis
Abstract
4,5-Diphenylisothiazol-3-ol has been prepared by reaction of phenylacetonitrile anion with sulphites. A tentative mechanism is proposed for the reaction. α-Cyano-α-(4,5-diphenylisothiazol-3-yl)benzyl phenyl thione (IV) and 4-imino-2,3,5-triphenylhex-2-enedinitrile (V) were also isolated from the reaction mixtures.