The action of isoxazol-5-ones on enamines
Abstract
The reaction of enamines with isoxazol-5-ones unsubstituted at the 4-position takes place in a manner similar to that with oxazol5-ones to give, in this case, the 4-alkenylisoxazol-5-olate salts of the appropriate amine. These salts are readily converted into the 4-alkylideneisoxazolones with hydrogen chloride. By using a mixture of ketone and base rather than the enamine, the same salts are obtained by a different mechanism.