Studies in the steroid group. Part LXXXII. The preparation of nine mono- and eight di-oxoandrostanes, 5α-estran-17-one, and 5α-pregnane-2,20-dione

Abstract

The following steroids, required as substrates for microbiological studies, have been prepared: 17α-hydroxy-2-oxo-, 7α-hydroxy-3-oxo-, 7β-hydroxy-3-oxo-,17β-hydroxy-7-oxo-, and 3β-acetyl-5α-androstane, 6β-hydroxyandrost-4-en-3-one, androst-5-en-7-one, 6β-hydroxy-3-oxo- and 6-oxo-5β-androstane, 2,7-, 3,6-, 3,7-, 3,12-, 7,17-, and 11,16-dioxo-5α-androstane, 3β-acetyl-17-oxo-5α-androstane, 5α-estran-17-one, and 5α-pregnane-2,20-dione. This work makes some diketones of the less common types available in reasonable quantity.