Conformation and reactivity in 2-chlorocyclobutanones: the rearrangement of 7-exo-chloro-7-isopropylbicyclo[3,2,0]hept-2-en-6-one
Abstract
Because of conformational effects in the cyclobutanone ring, 7-exo-chloro-7-isopropylbicyclo[3,2,0]-hept-2-en-6-one rearranges abnormally on base treatment and gives three hydroxycyclohexenecarboxylic acids: a possible mechanism involves ketol rearrangements.
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