Issue 17, 1972

Conformation and reactivity in 2-chlorocyclobutanones: the rearrangement of 7-exo-chloro-7-isopropylbicyclo[3,2,0]hept-2-en-6-one

Abstract

Because of conformational effects in the cyclobutanone ring, 7-exo-chloro-7-isopropylbicyclo[3,2,0]-hept-2-en-6-one rearranges abnormally on base treatment and gives three hydroxycyclohexenecarboxylic acids: a possible mechanism involves ketol rearrangements.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1972, 997-998

Conformation and reactivity in 2-chlorocyclobutanones: the rearrangement of 7-exo-chloro-7-isopropylbicyclo[3,2,0]hept-2-en-6-one

P. R. Brook and J. M. Harrison, J. Chem. Soc., Chem. Commun., 1972, 997 DOI: 10.1039/C39720000997

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