Issue 14, 1972

Intramolecular nucleophilic aromatic substitution reactions involving the novel displacement of hydride ion by cyanobenzyl carbanions

Abstract

α-(N-Substituted-N-3,5-dinitrobenzoylamino)-, α-(N-substituted-N-2-chloro-3,5-dinitrobenzoylamino)-, and α-(N-substituted-N-3-nitrobenzoylamino)phenylacetonitriles (1) and (2) undergo base-catalysed cyclisation with displacement of hydride ion or chloride ion to afford the corresponding isoindolin-1-ones (3), (4), and (5).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1972, 849-850

Intramolecular nucleophilic aromatic substitution reactions involving the novel displacement of hydride ion by cyanobenzyl carbanions

D. W. Bayne, G. Tennant and T. W. M. Spence, J. Chem. Soc., Chem. Commun., 1972, 849 DOI: 10.1039/C39720000849

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