Experiments on the synthesis of tetracycline. Part VII. The total synthesis of 6-methylpretetramid
Abstract
Application of the photocyclisation procedure described in Part V to ring A substituted compounds is discussed. The photocyclisation product methyl 12-ethylenedioxy-6aα,7,12,12aα-tetrahydro-9,11-dimethoxy-6-oxo-1-phenyl-6H-naphthaceno[1,12-bc]furan-10-carboxylate (XII; R1= Me, R2= OMe, X = Y = O) has been converted into 6-methylpretetramid.