A convenient synthesis of 3-furoic acid and 3-acetylfuran
Abstract
Reaction of 4-phenyloxazole with propiolic acid gave 3-furoic acid (37%); reaction of 4-phenyloxazole with ethynyl methyl ketone gave 3-acetylfuran (41%). No Diels–Alder reaction was detected between the acetylenes and 1,3,4-oxadiazole.