The synthesis and biological evaluation of flexible oestrone analogues, for example trans-3-p-methoxystyryl-2-methylcyclopentan-1-one (VIII), are described. The mass spectral fragmentation of these model compounds is discussed in the context of the similar breakdown observed for the related steroidal molecules.
G. Jones, J. Chem. Soc. C, 1971, 922 DOI: 10.1039/J39710000922
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