Polyhalogenoaromatic compounds. Part XVII. Synthesis of arylpentachlorophenyl ketone imines and 2,4-diaryl-5,6,7,8-tetrachloroquinazolines by the reaction of pentachlorophenyl-lithium with nitriles

Abstract

The addition of pentachlorophenyl-lithium to aromatic nitriles gives N-lithio-arylpentachlorophenylketone imines. Hydrolysis of the N-lithio-imines gives the free imines as mixtures of syn- and anti-isomers, and reaction with dimethyl sulphate gives the N-methyl derivatives.

With an excess of the nitrile, pentachlorophenyl-lithium give 2,4-diaryl-5,6,7,8-tetrachloroquinazolines.