Synthesis and some reactions of 3-substituted 10bH-oxazolo[3,2-c][1,3]benzoxazine-2(3H),5-diones
Abstract
A simple two-stage synthesis of a number of 3-substituted 10bH-oxazolo[3,2-c][1,3]benzoxazine-2(3H),5-diones is described. These materials react with primary amines to form α-ureido-carboxamides, with concomitant elimination of a mixture of salicylaldehyde and the corresponding Schiff base with the primary amine. 3,5-Disubstituted hydantions are formed by alkaline hydrolysis of the ureido-carboxamides.