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Issue 18, 1971
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4-Alkyl-thio- and -dithio-azetidinones from penicillins

Abstract

Thiols react smoothly with penicillin sulphoxides to form 4-alkylthioazetidinones which, by treatment with phosphites or reaction with nucleophiles and alkyl iodides, afford 4-alkylthioazetidinones; some related reactions are also reported.

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Article type: Paper
DOI: 10.1039/C29710001137
J. Chem. Soc. D, 1971, 1137-1139

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    4-Alkyl-thio- and -dithio-azetidinones from penicillins

    D. H. R. Barton, P. G. Sammes, M. V. Taylor, C. M. Cooper, G. Hewitt, B. E. Looker and W. G. E. Underwood, J. Chem. Soc. D, 1971, 1137
    DOI: 10.1039/C29710001137

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