Issue 16, 1971

The absolute stereochemistry of α-methylation in benzyl methyl sulphoxide

Abstract

Electrophilic substitution of benzyl methyl sulphoxide with methyl iodide has been shown to proceed with high stereoselectivity and with retention of the configuration (in tetrahydrofuran), in striking contrast to the partial deuteriation which appears to proceed with inversion.

Article information

Article type
Paper

J. Chem. Soc. D, 1971, 958-959

The absolute stereochemistry of α-methylation in benzyl methyl sulphoxide

K. Nishihata and M. Nishio, J. Chem. Soc. D, 1971, 958 DOI: 10.1039/C29710000958

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