Issue 15, 1971
From the journal:

Journal of the Chemical Society D: Chemical Communications

General methods of alkaloid synthesis. A new approach to functionalized hydrolulolidone Aspidosperma alkaloid precursors. A formal synthesis of (±)-aspidospermine

R. V. Stevens,   J. Michael Fitzpatrick,   Morris Kaplan  and  Robert L. Zimmerman  

Abstract

A new method for the synthesis of an established hydrolulolidone Aspidosperma alkaloid precursor, (4), is presented which involves the acid-catalysed thermal rearrangement of a cyclopropyl-imine (10) to a 2-pyrroline (11) as a key stage.

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Article information

DOI
https://doi.org/10.1039/C29710000857
Article type
Paper

J. Chem. Soc. D, 1971, 857-858

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General methods of alkaloid synthesis. A new approach to functionalized hydrolulolidone Aspidosperma alkaloid precursors. A formal synthesis of (±)-aspidospermine

R. V. Stevens, J. M. Fitzpatrick, M. Kaplan and R. L. Zimmerman, J. Chem. Soc. D, 1971, 857 DOI: 10.1039/C29710000857

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