Issue 9, 1971

Epimerisation of penicillanic acid derivatives and their rearrangement to 1,4-thiazepines: evidence for an E1cB mechanism

Abstract

A common enolate-like intermediate is implicated in the weak base-catalysed conversion of methyl 6β-phthalimidohomopenicillanate into methyl 6α-phthal-imidohomopenicillanate and methyl 2,3,4,7-tetrahydro-2,2-dimethyl-7-oxo-6-phthalimido-1,4-thiazepine-3(S)-acetate.

Article information

Article type
Paper

J. Chem. Soc. D, 1971, 450-452

Epimerisation of penicillanic acid derivatives and their rearrangement to 1,4-thiazepines: evidence for an E1cB mechanism

B. G. Ramsay and R. J. Stoodley, J. Chem. Soc. D, 1971, 450 DOI: 10.1039/C29710000450

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