A method is described for the preparation of pyrrole derivatives from pyrimidines by ring contraction with zinc in 50% aqueous acetic acid. Evidence for the structure of the pyrroles, and for the 3,4-dihydropyrimidines produced as by-products, is presented. Possible reaction mechanisms are discussed.
J. L. Longridge and T. W. Thompson, J. Chem. Soc. C, 1970, 1658 DOI: 10.1039/J39700001658
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