A Friedel–Crafts reaction between 2,6-dimethoxybenzoyl chloride and benzene yields 2,6-dimethoxybenzophenone and 3-benzoyl-2,2′,4,6′-tetramethoxybenzophenone, and under milder conditions, 3-carboxy-2,2′,4,6′-tetramethoxybenzophenone. A synthesis and the degradation under acid conditions of 3-benzoyl-2,2′,4,6′-tetramethoxybenzophenone are described.
P. Fletcher and W. Marlow, J. Chem. Soc. C, 1970, 937 DOI: 10.1039/J39700000937
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