Activation parameters for conformational isomerism in an N-acetylpyrrolidine by total nuclear magnetic resonance line shape analysis and direct thermal stereomutation

Abstract

Additional experimental evidence supporting total n.m.r. line shape analysis for obtaining activation parameters results from a comparison of rate data derived from the direct equilibration at low temperatures of a conformationally pure rotamer of (I) and rate data from a total n.m.r. line shape analysis at higher temperatures.