Hydropyrimidines. Part VIII. Reactions of some dihydropyrimidines and their thio-derivatives with nucleophiles
Abstract
Thio-analogues of 5,6-dihydrouracil and its methyl derivatives (I) showed characteristic reactivities towards nucleophiles, yielding ureas (II), carbamates (IV), and dimethoxy-derivatives (VI), when treated with methoxide ion. These reactions are affected by the nature and position of the substituents in the dihydropyrimidines.