Issue 18, 1969

Organolithium chemistry of N-heterocycles. Part I. Action of phenyllithium on 2-methylpyridines and 2-methylquinolines

Abstract

Reaction of phenyl-lithium and 2-methylquinoline in diethyl ether gives, to the exclusion of azomethine addition, 90% side-chain metallation. Analogous compounds containing activated 2-methyl groups react similarly, except that 2,4-lutidine produced 2,4-dimethyl-6-phenylpyridine.

Article information

Article type
Paper

J. Chem. Soc. C, 1969, 2245-2246

Organolithium chemistry of N-heterocycles. Part I. Action of phenyllithium on 2-methylpyridines and 2-methylquinolines

A. M. Jones, C. A. Russell and S. Skidmore, J. Chem. Soc. C, 1969, 2245 DOI: 10.1039/J39690002245

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