Addition reactions of heterocyclic compounds. Part XXXIX. 2-Phenyl-ethynylpyridine and related pyridines with acetylenic esters

Abstract

Denydrobromination of 2-styrylpyridine (stilbazole) dibromide with potassium t-butoxide yielded 2-phenylethy pyridine, which with dimethyl acetylenedicarboxylate gave tetramethyl oxybis-1-phenylmethylene-indolizine-2,3-dicarboxylate. The products from reaction of the acetylene with 2-styrylpyridine dibromide, 2(1H)-pyridylmethyleacetophenone, and α-(2-pyridyl)acetophenone, and from reaction of methyl propiolate with α-(2-pyridyl)acetophenone, were identified.