Some reactions of 3-hydroxyimino-2,4-dimethyl-1,5-benzodiazepine

Abstract

The reaction of 3-hydroxyimino-2,4-dimethyl-1,5-benzodiazepine with acyl-, thioacyl-, and aryl-hydrazines yields hydrazono-derivatives of 2-acetyl-3-methylquinoxaline. By-products of the reaction indicate that the mechanism involves complete fission of the diazepine ring.

The conditions under which the syn- and anti-oximes of 2-acetyl-3-methylquinoxaline are formed from 3-hydroxyimino-2,4-dimethyl-1,5-benzodiazepine on treatment with hydroxylamine hydrochloride, are discussed.