Synthesis of 1β-methyl-9β,10α-19-norsteroids
Abstract
The synthesis of 1β-methyl-5α,10α-oestrane derivatives is reported. It is shown that 1β-methyl-11-oxo-5α,9α,10α-19-norsteroids are easily epimerized at C-9, thus providing a new route to retro-steroids.