The preparation of the enantiomers of cis- and trans-2-dimethylaminocyclohexylacetate methiodide (potential substrates for the enzyme acetylcholinesterase) is reported. The absolute configuration of the cis-enantiomers has been shown from their relationship with compounds of known configuration. The configuration of the trans-enantiomers is inferred from o.r.d. spectral studies.
J. B. Kay and J. B. Robinson, J. Chem. Soc. C, 1969, 248 DOI: 10.1039/J39690000248
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