Issue 10, 1969

The role of substrate structure in the initiation of enzymic cyclization of squalene 2,3-oxide. Stereochemistry of homosterol formation from 1-methylsqualene 2,3-oxide

Abstract

Squalene 2,3-oxide lanosterol cyclase selectively converts the 1′-cis-methyl isomer as a component in a mixture of cis- and trans-1-methylsqualene 2,3-oxides into 4α-ethyl-4β,14α-dimethylcholesta-8,24-dien-3β-ol.

Article information

Article type
Paper

J. Chem. Soc. D, 1969, 532-533

The role of substrate structure in the initiation of enzymic cyclization of squalene 2,3-oxide. Stereochemistry of homosterol formation from 1-methylsqualene 2,3-oxide

L. O. Crosby, E. E. van Tamelen and R. B. Clayton, J. Chem. Soc. D, 1969, 532 DOI: 10.1039/C29690000532

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