Issue 0, 1968

Quinazolines and 1,4-benzodiazepines. Part XXXVIII. The reaction of hydrazines with 6-chloro-2-chloromethyl-4-phenylquinazoline 3-oxide

Abstract

The reactions of hydrazines with 6-chloro-2-chloromethyl-4-phenylquinazoline 3-oxide have been investigated. In the case of hydrazine, a benzodiazepine was obtained, and some of its reactions with acetylating agents are discussed. When 1,1-dimethylhydrazine and methylhydrazine were used, quinazoline hydrazones were obtained. A mechanism is suggested.

Article information

Article type
Paper

J. Chem. Soc. C, 1968, 1103-1105

Quinazolines and 1,4-benzodiazepines. Part XXXVIII. The reaction of hydrazines with 6-chloro-2-chloromethyl-4-phenylquinazoline 3-oxide

M. E. Derieg, R. I. Fryer and L. H. Sternbach, J. Chem. Soc. C, 1968, 1103 DOI: 10.1039/J39680001103

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