Unsymmetrically disubstituted ferrocenes. Part V. Addition and metallation in the reaction of n-butyl-lithium with 2-ferrocenylpyridine

Abstract

2-Ferrocenylpyridine was rapidly and specifically lithiated by n-butyl-lithium at room temperature in the 2-position of the ferrocene ring; this was followed by the slow addition of the reagent to the carbon–nitrogen double bond. The lithio-amine products were characterised after (a) hydrolysis and (b) reaction with benzophenone followed by hydrolysis.