The synthesis and properties of analogues of angiotensin modified in the 1- or the 4-position
Abstract
The synthesis and properties of 1-L-(γ)glutamic acid-5-L-valine angiotensin II, 1-L-(α)glutamic acid-5-L-valine angiotensin II, 1-L-asparagine-4-L-(α)glutamic acid-5-L-valine angiotensin II, and 1-L-asparagine-4-L-O-methyltyrosine-5-L-valine angiotensin II are described. 1-L-Pyroglutamic acid-5-L-valine angiotensin II was prepared by heating the 1-(α)glutamic acid analogue in aqueous solution.