Issue 0, 1967

Partially fluorinated heterocyclic compounds. Part III. The preparation of 4,5,6,7-tetrafluorobenzo[b]furan

Abstract

4,5,6,7-Tetrafluoro-2,3-dihydrobenzo[b]furan-3-one has been prepared by the cyclisation and decarboxylation of ethyl 6-ethoxycarbonyl-2,3,4,5-tetrafluorophenoxyacetate and by the reaction of 2,3,4,5-tetrafluorophenoxyacetic acid with butyl-lithium followed by carbonation. Reduction and dehydration of the benzo[b]furan-3-one gave 4,5,6,7-tetrafluorobenzo[b]furan. The attempted electrophilic cyclisation reactions of 2,3,4,5-tetrafluorophenoxy-acetic acid, -acetyl chloride, and -acetaldehyde diethyl acetal are reported.

Article information

Article type
Paper

J. Chem. Soc. C, 1967, 869-873

Partially fluorinated heterocyclic compounds. Part III. The preparation of 4,5,6,7-tetrafluorobenzo[b]furan

G. M. Brooke and B. S. Furniss, J. Chem. Soc. C, 1967, 869 DOI: 10.1039/J39670000869

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